Zoloft is prescribed to patients suffering from a variety of mental or other disorders. This antidepressant works by affecting certain chemicals in the brain that cause depression, anxiety and other symptoms. This medicine should not be taken with pimozide or monoamine oxidase inhibitors as dangerous drug interaction can occur. There should be a pause of at least two weeks between any MAOI inhibitor (such as isocarboxazid, phenelzine, rasagiline, selegiline, or tranylcypromine) and Zoloft. During the first 12 weeks of treatment your doctor will have you under close observation as during this period some patients develop suicidal thoughts and other potentially dangerous side effects.
This drug is not intended to treat depression in children. If you notice your symptoms are worsening, call your doctor immediately. Possible signs may include mood swings, irritability, agitation, hostility, aggressiveness, restlessness, mental or physical hyperactivity, suicidal thoughts, panic attacks, and trouble sleeping. You should inform your doctor of using any of the following medicines: sleeping pills, pain medicines, muscle relaxants, medicine for anxiety or seizures, as well as cold or allergy remedies.